Thorne's Glutathione is NSF Certified for Sport®. It occurs naturally in cells and is a cofactor in dozens of enzymatic reactions involved in detoxification.* As an antioxidant, glutathione directly quenches several reactive oxygen species (free radicals).* The body's benefits from maintaining a normal level of glutathione include support for liver function, pulmonary function, immune function, bowel health, carbohydrate metabolism, cardiovascular health, cognitive health, and eye health.* Glutathione-SR is a breakthrough in glutathione supplementation because its sustained-release formula protects it from stomach acid and digestive enzymes, allowing for a slower release and a more steady level in the bloodstream of this essential nutrient.*

Glutathione is the most abundant anti-oxidant. Since training and competition create more oxidative stress and damage, athletes have a higher need for antioxidants. Exercise longer than 60-90 minutes significantly decreases glutathione levels in the blood, so supplementing is beneficial for endurance and ultra endurance events.

The liver is the body's largest reservoir for glutathione. A potent endogenous antioxidant, glutathione is essential for the liver's phase I and phase II detoxification.* However, negative lifestyle issues and adverse conditions that affect liver health can result in a decreased amount of glutathione in the liver.

Maintaining an optimal level of glutathione appears to be important for supporting cognitive function, especially during aging.* The normal process of aging is associated with a decrease in glutathione activity, which can result in increased oxidative activity.* Less than an optimum level of glutathione is observed in individuals experiencing a decline in cognitive function.* Conversely, individuals who live to 100 tend to have higher glutathione activity.*

Although a common mistaken belief is that glutathione is not well absorbed when it's taken orally, significant data confirms that glutathione is efficiently absorbed across the intestinal epithelium by a specific uptake system.*

Because an athlete needs to know that his or her supplements are trustworthy and compliant, every batch of an NSF Certified for Sport® product is tested for compliance with label claims and to ensure the absence of more than 200 substances banned by many major athletic organizations, including stimulants, narcotics, steroids, diuretics, beta-2 agonists, and masking agents.

Aging is a fact for every baby boomer and Gen-X’er. Although no supplement truly has "anti-aging" properties, ResveraCel comes close because it supports cellular repair, up-regulates the sirtuin proteins, enhances NAD+ production, and benefits the cellular energy production that takes place in the mitochondria – thus supporting the process of healthy aging.*

Adding ResveraCel to your daily supplement regimen can make a positive impact on aging and support good health as you get older.*

Benefits of Thorne’s ResveraCel:

• Supports healthy cellular aging*
• Natural activator of the sirtuin proteins, an important class of protein enzymes that act as cellular switches to up-regulate numerous positive functions associated with aging*
• Helps clean the body of old cells, by assisting with the elimination of aging cells (inactive, senescent)*
• Supports optimal mitochondrial number, structure, and function*
• Supports healthy methylation*
• Enhances cellular energy production*
• Promotes healthy metabolism as you age*
• Benefits healthy blood sugar and insulin sensitivity*
• Supports fat metabolism in the liver*

Take an inside look at the intelligent ingredients in ResveraCel and their beneficial impacts on healthy aging:

Nicotinamide Riboside Hydrogen Malate (NR)

NAD+ – nicotinamide adenine dinucleotide – is an important coenzyme found in every cell that plays an integral role in multiple body functions. Because the body’s natural level of NAD+ begins to decline significantly with age, it can lead to adverse effects of aging and age-related conditions. As a direct precursor to NAD+, NR efficiently stimulates the production of NAD+, which:

• Promotes multiple aspects of healthy aging*
• Supports cellular repair processes*
• Protects against DNA damage and oxidative stress*
• Promotes exercise efficiency, helping to support health and fitness goals*
• Helps maintain an optimal state of health*
• Promotes the number and health of the mitochondria in cells, benefiting mitochondrial metabolism*

• Supports normal circadian rhythm function*

Resveratrol

Resveratrol, a natural substance found in, among other things, red wine, has shown promise in clinical studies by modulating the effects of several age-related conditions, including:

• Supporting the body's normal inflammatory response and its health-promoting effect on blood vessels*
• Activating a special class of protein enzymes called sirtuins that act as cellular switches by up-regulating numerous positive functions, including cellular aging, inflammatory response, detoxification, stress resistance, fat and glucose metabolism, circadian rhythm, and mitochondrial biogenesis*
• The sirtuin proteins support the formation of new mitochondria in the cells, which results in more efficient cellular energy production and possibly increased longevity*

Quercetin Phytosome

Senescence is the natural process in which aging cells stop dividing, but do not die. The over-accumulation of senescent cells is associated with biological aging and various age-related disorders. Quercetin is at the forefront of healthy aging because:

• Quercetin is one of only two nutrients that have been studied for its ability to reduce cellular senescence*
• Quercetin partners with resveratrol in the quest for healthy aging because it slows the breakdown of resveratrol in the body, allowing resveratrol more time to do its job*
• Quercetin up-regulates the sirtuin proteins, which are associated with healthy cellular aging and improved weight-related metabolic factors*

 Betaine

To achieve NR’s optimal benefit, it is important to support the body’s methylation processes. Betaine is a premiere methyl donor because:

• Betaine (also called trimethylglycine) is a superior nutrient for donating its methyl groups – compounds that help produce healthy DNA, neurotransmitters, and cellular energy*
• In female athletes, research indicates that betaine promotes lean body composition by helping to reduce body fat without negatively affecting muscle mass*
• Betaine supports the body’s ability to engage in higher volume exercise – increased repetitions and weight load in male athletes and improved high volume work capacity in female athletes*

The cells that make up the heart muscle have a very high metabolism and need CoQ10 as an energy-producing cofactor.* Numerous studies on CoQ10 have shown its benefit in cardiovascular function.* It also serves as an antioxidant.*

Thorne's Heart Health Complex combines CoQ10 with taurine, an amino acid that research indicates can support already normal levels of cholesterol, and which, by aiding in the regulation of intracellular calcium levels, helps protect the heart muscle and support cardiac rhythm.* The flavonoid compounds in hawthorn (Crataegus oxycantha) appear to strengthen blood vessels and support cardiac function.* Hawthorn has also been shown to help maintain already normal blood pressure, heart rate, and exercise capacity.* The minerals in Heart Health Complex – magnesium and potassium – are necessary for optimal cardiovascular function.*

Numerous studies on CoQ10 indicate its benefit in cardiovascular function.* In a 73-subject study supplementing CoQ10 at 120 mg daily, improvements in cardiovascular function were observed after 28 days.*

The flavonoids in hawthorn also act as antioxidants and provide support for artery function.*

Taurine is an essential nutrient cofactor for cardiac function and rhythm, and is the most abundant amino acid in the heart.* Taurine's support for already normal levels of cholesterol is probably due to its ability to facilitate the conversion of cholesterol to bile acids.*

Astaxanthin is an extremely powerful carotenoid from the microalgae Haematococcus pluvialis, which is one of the richest sources of natural astaxanthin. It is reddish in pigment and it is what gives crustaceans, such as krill, lobster, shrimp, and salmon, their vibrant pink color. Astaxanthin is a uniquely structured, long-chain molecule that enables it to provide superior membrane protection, and it is considered to be substantially stronger than all other well-researched antioxidants. Its impressive antioxidant properties benefit the body in many ways, which include offering support for cardiovascular, gastrointestinal (GI), skin, and eye health.* The astaxanthin in this product is extracted directly from microalgae using a solvent-free technology that ensures maximum control and purity, and allows for optimal bioavailability and stability.

Mito-PQQ™ is designed to help support optimal mitochondrial biogenesis, which involves the formation of new mitochondria, a critical process for the promotion of healthy aging, energy production, and antioxidative status in the body.* Mito-PQQ™ features pyrroloquinoline quinone (PQQ), a water-soluble, vitamin-like compound, and Rhodiola rosea, a well-known adaptogen. PQQ is an enzyme cofactor that possesses antioxidant properties and supports cardiovascular and brain health by encouraging the formation of new mitochondria.* Rhodiola rosea supports adrenal gland health, helps the body adapt to stress, and helps promote mitochondrial energy production.

We use NAD every day for basic functions like sleeping, breathing, eating, and drinking. But our NAD levels decline with age and metabolic stress which contributes to changes in health. Tru Niagen® increases your NAD, every time you take it.*

Tru Niagen® is a specialized form of vitamin B3 discovered by our Chief Scientific Advisor Charles Brenner, PhD, and developed specifically to increase NAD more effectively than any other B3 before it. Our key ingredient uses a unique pathway to increase NAD, with evidence to support it works better than either Niacin or NAM (nicotinamide / niacinamide)